Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961810 | 0.92 | AVPR2 (0.39) | ABCB1ABCG2ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7964094 | 0.91 | AVPR2 (0.39) | ABCB1ABCG2ADRA1DADRA1AADRA1B | |
| SCHEMBL7967025 | 0.90 | MAPT (0.39) | ABCB1ABCG2ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7480503 | 0.89 | MAPT (0.39) | ABCB1ABCG2ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7966083 | 0.89 | ABCB1 (0.37) | ABCB1ABCG2ADRA1DADRA1AADRA1B | |
| SCHEMBL7954335 | 0.85 | MAP3K7 (0.34) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL7482003 | 0.84 | MAP3K7 (0.33) | ABCB1ABCG2MEN1KMT2AUSP2 | |
| SCHEMBL7342048 | 0.84 | LMNA (0.38) | MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7778669 | 0.84 | LMNA (0.37) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7964770 | 0.84 | MAP3K7 (0.33) | ABCB1ABCG2ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |