Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325450 | 0.85 | TSHR (0.51) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22564938 | 0.84 | TSHR (0.46) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3891985 | 0.84 | TSHR (0.54) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30746861 | 0.82 | ALOX15 (0.55) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL176214 | 0.82 | ALOX15 (0.55) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7583697 | 0.81 | TSHR (0.56) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19686190 | 0.81 | TSHR (0.48) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1280719 | 0.81 | ALOX15 (0.53) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31124708 | 0.81 | ALOX15 (0.53) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11245928 | 0.81 | TSHR (0.51) | TSHRNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277878-B1 | ANTIINFLAMMATORY AGENTS; ANALGESICS | PFIZER INC | 2001-08-21 | — | — | US | disclosed |