Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.34 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CD4 | P01730 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1419569 | 1.00 | NPSR1 (0.36) | NPSR1ALDH1A1LMNAUSP2GAA | |
| SCHEMBL1417531 | 0.83 | ALDH1A1 (0.36) | NPSR1ALDH1A1LMNAUSP2GAA | |
| SCHEMBL1417529 | 0.83 | ALDH1A1 (0.36) | NPSR1ALDH1A1LMNAUSP2GAA | |
| SCHEMBL1419555 | 0.81 | KMT2A (0.37) | NPSR1ALDH1A1LMNAUSP2GAA | |
| SCHEMBL12677395 | 0.81 | KMT2A (0.37) | NPSR1ALDH1A1LMNAUSP2GAA | |
| SCHEMBL12670985 | 0.77 | KDM2B (0.38) | ALDH1A1POLBPKMKDM2BKMT2A | |
| SCHEMBL1417900 | 0.74 | ESR2 (0.45) | ALDH1A1LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL7985524 | 0.73 | ALDH1A1 (0.39) | ALDH1A1LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL12670982 | 0.73 | ALDH1A1 (0.39) | ALDH1A1LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL7987996 | 0.65 | ALDH1A1 (0.39) | NPSR1ALDH1A1LMNAUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298747-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-03-23 | — | — | EP | disclosed |
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |