Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.33 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417900 | 0.84 | ESR2 (0.45) | ALDH1A1GAAUSP2LMNASMN1; SMN2 | |
| SCHEMBL7974244 | 0.80 | KMT2A (0.37) | ALDH1A1GAAUSP2LMNASMN1; SMN2 | |
| SCHEMBL1417529 | 0.74 | ALDH1A1 (0.36) | ALDH1A1GAAUSP2LMNASMN1; SMN2 | |
| SCHEMBL1417531 | 0.74 | ALDH1A1 (0.36) | ALDH1A1GAAUSP2LMNASMN1; SMN2 | |
| SCHEMBL7969583 | 0.73 | NPSR1 (0.36) | ALDH1A1GAAUSP2LMNASMN1; SMN2 | |
| SCHEMBL1419569 | 0.73 | NPSR1 (0.36) | ALDH1A1GAAUSP2LMNASMN1; SMN2 | |
| SCHEMBL12670982 | 0.73 | ALDH1A1 (0.39) | ALDH1A1GAAUSP2LMNASMN1; SMN2 | |
| SCHEMBL12670985 | 0.70 | KDM2B (0.38) | ALDH1A1KMT2ANPC1MAPTMEN1 | |
| SCHEMBL7987717 | 0.67 | HTR6 (0.46) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL7987996 | 0.65 | ALDH1A1 (0.39) | ALDH1A1GAAUSP2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |