Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | AOC2 | O75106 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527141 | 1.00 | AOC3 (0.55) | AOC3LTA4HTSHRTAAR1PLA2G2A | |
| SCHEMBL9501302 | 0.94 | LTA4H (0.50) | AOC3LTA4HTSHRPLA2G2AMAOB | |
| SCHEMBL326201 | 0.82 | MAOB (0.57) | AOC3LTA4HMAOBMAOA | |
| SCHEMBL11301704 | 0.79 | TAAR1 (0.41) | AOC3LTA4HTSHRTAAR1PLA2G2A | |
| SCHEMBL8572677 | 0.78 | IDO1 (0.53) | AOC3LTA4HTSHRTAAR1PLA2G2A | |
| SCHEMBL11541789 | 0.78 | LTA4H (0.45) | AOC3LTA4HTSHRTAAR1MAOB | |
| SCHEMBL11541783 | 0.78 | LTA4H (0.45) | AOC3LTA4HTSHRTAAR1MAOB | |
| SCHEMBL10785857 | 0.77 | LTA4H (0.42) | AOC3LTA4HTSHRTAAR1PLA2G2A | |
| SCHEMBL4632159 | 0.77 | LTA4H (0.43) | AOC3LTA4HTSHRMAOAKCNA3 | |
| SCHEMBL5513094 | 0.77 | LTA4H (0.43) | AOC3LTA4HTSHRKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262078-B1 | Phenoxymethyl piperidine derivatives for the treatment of neuropathic pain | SYNTEX (U.S.A.) LLC | 2001-07-17 | — | — | US | disclosed |
| US-6110937-A | A SODIUM CHANNEL BLOCKER TREATING AS LOCAL ANESTHETICS AND IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | SYNTEX USA, INC. (US) | 2000-08-29 | — | — | US | disclosed |
| EP-0869119-A1 | Phenoxymethyl piperidine derivatives being sodium channle blockers | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-07 | — | — | EP | disclosed |