SCHEMBL527141

SCHEMBL527141

NCC=COc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 4/20 0.55
LTA4H P09960 2/20 0.42
TSHR P16473 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
PLA2G2A P14555 1/20 0.41
MAOB P27338 4/20 0.40
HRH1 P35367 1/20 0.38
MAOA P21397 3/20 0.38
AOC2 O75106 2/20 0.36
DAO P14920 1/20 0.36
KCNA3 P22001 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7969598 1.00 AOC3 (0.55) AOC3LTA4HTSHRTAAR1PLA2G2A
SCHEMBL9501302 0.94 LTA4H (0.50) AOC3LTA4HTSHRPLA2G2AMAOB
SCHEMBL326201 0.82 MAOB (0.57) AOC3LTA4HMAOBMAOA
SCHEMBL11301704 0.79 TAAR1 (0.41) AOC3LTA4HTSHRTAAR1PLA2G2A
SCHEMBL8572677 0.78 IDO1 (0.53) AOC3LTA4HTSHRTAAR1PLA2G2A
SCHEMBL11541789 0.78 LTA4H (0.45) AOC3LTA4HTSHRTAAR1MAOB
SCHEMBL11541783 0.78 LTA4H (0.45) AOC3LTA4HTSHRTAAR1MAOB
SCHEMBL10785857 0.77 LTA4H (0.42) AOC3LTA4HTSHRTAAR1PLA2G2A
SCHEMBL4632159 0.77 LTA4H (0.43) AOC3LTA4HTSHRMAOAKCNA3
SCHEMBL5513094 0.77 LTA4H (0.43) AOC3LTA4HTSHRKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2498746-B1 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES UNILEVER PLC NO 41424 (GB) 2016-08-24 EP claimed
US-8309064-B2 Skin care compositions comprising phenoxyalkyl amines CONOPCO, INC. (US) 2012-11-13 US claimed
EP-2498746-A2 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2012-09-19 EP claimed
CN-102686212-A Skin care compositions comprising phenoxyalkyl amines UNILEVER PLC 2012-09-19 CN claimed
WO-2011054804-A2 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES UNILEVER PLC (GB) 2011-05-12 WO claimed
US-20110110870-A1 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES CONOPCO, INC., D/B/A UNILEVER (US) 2011-05-12 US claimed
WO-2010004016-A1 USE OF PHENOXYALKYLAMINES IN COSMETIC AND/OR DERMATOLOGICAL COMPOSITIONS L'OREAL (FR) 2010-01-14 WO claimed
EP-0618195-B1 Insecticidal, acaricidal and fungicidal pyrazole phenoxyalkylamin derivatives and process for preparing the same UBE INDUSTRIES (JP) 1997-06-04 EP claimed
CN-1031639-C Phenoxyalkylamine compound and its preparing method UNIV CHINA PHARMACY (CN) 1996-04-24 CN claimed
US-5409957-A Phenoxyalkylamine and agricultural and horticultural bactericide MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-04-25 US claimed
EP-0429314-A2 Phenoxyalkylamine and agricultural and horticultural bactericide MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1991-05-29 EP claimed
EP-0405808-A1 Phenoxyalkylamine derivatives and insecticides, acaricides and fungicides UBE INDUSTRIES, LTD. (JP) 1991-01-02 EP claimed
US-4753674-A PLANT GROWTH REGULATORS UBE INDUSTRIES, LTD. (JP) 1988-06-28 US claimed
EP-0186275-A2 2-Substituted amino-4(1H)-pyrimidone derivatives, their production, and medical compositions containing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-07-02 EP claimed
US-4225608-A ANTIDEPRESSANTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1980-09-30 US claimed
EP-0004288-A2 Phenoxyalkyl amines, pharmaceutical compositions containing them, and process for their preparation MERCK PATENT GmbH (DE) 1979-10-03 EP claimed
US-4038319-A SUBSTITUTED PHENOXYALKYLAMINES, PROCESS FOR THEIR PREPARATION AND APPLICATIONS THEREOF LABORATOIRES LAROCHE NAVARRON (FR) 1977-07-26 US claimed
US-3988475-A ANAESTHETICS, ANTIARRHYTHMIA, HYPOTENSIVES, ADRENERGIC ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) 1976-10-26 US claimed
US-3979456-A Phenoxyalkylamines, process for their preparation and applications thereof LABORATOIRES LAROCHE NAVARRON (FR) 1976-09-07 US claimed
US-3959359-A VASODILATORS LABORATOIRES LAROCHE NAVARRON (FR) 1976-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110110870-A1 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES CUTA, TYR, FLNA AOC3 140/4885LTA4H 645/4885TSHR 4502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.