Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573955 | 0.84 | TSHR (0.48) | HTTMAPTAKR1B1KDM4EPKM | |
| SCHEMBL1620183 | 0.83 | NFE2L2 (0.54) | HTTLMNAMAPTAKR1B1KDM4E | |
| SCHEMBL7971332 | 0.83 | GAA (0.50) | HTTLMNAMAPTAKR1B1KDM4E | |
| SCHEMBL7958580 | 0.79 | KMT2A (0.44) | KDM4EPKMALDH1A1MEN1KMT2A | |
| SCHEMBL1619865 | 0.79 | NFE2L2 (0.57) | HTTLMNAMAPTAKR1B1KDM4E | |
| SCHEMBL7974892 | 0.72 | KMT2A (0.64) | HTTLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9174593 | 0.72 | NFE2L2 (0.44) | HTTMAPTKDM4EPKMALDH1A1 | |
| Lithium Ion SCHEMBL9176164 | 0.72 | NFE2L2 (0.44) | HTTMAPTKDM4EPKMALDH1A1 | |
| Potassium Ion SCHEMBL9175274 | 0.72 | NFE2L2 (0.44) | HTTMAPTKDM4EPKMALDH1A1 | |
| SCHEMBL4016427 | 0.71 | PKM (0.69) | HTTLMNAMAPTAKR1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |