Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407414 | 0.73 | ALOX5 (0.58) | LMNAALOX5 | |
| SCHEMBL7969537 | 0.71 | LMNA (0.37) | LMNAALOX5 | |
| SCHEMBL27532209 | 0.71 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9597226 | 0.68 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL7969806 | 0.67 | ALOX5 (0.50) | LMNAALOX5 | |
| Biphenyl SCHEMBL27435087 | 0.65 | LMNA (0.48) | LMNAALOX5 | |
| SCHEMBL7969404 | 0.64 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL7969402 | 0.64 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL7973050 | 0.64 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL16113017 | 0.64 | AKR1C3 (0.40) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291520-B1 | INHIBIT THE ENZYME LIPOXYGENASE; TREATMENT OR ALLEVIATION OF INFLAMMATORY DISEASES, ALLERGIC CONDITIONS AND CARDIOVASCULAR DISEASES | PFIZER | 2001-09-18 | — | — | US | disclosed |
| EP-0559743-B1 | NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE | PFIZER (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0559743-A1 | NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE. | PFIZER HOSPITAL PROD (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009566-A1 | NOVEL HYDROXAMIC ACID AND N-HYDROXYUREA DERIVATIVES AND THEIR USE | PFIZER INC. (US) | 1992-06-11 | — | — | WO | disclosed |