SCHEMBL7970101

SCHEMBL7970101

O=C(O)/C=C/c1ccc(-c2ccc(OC(F)(F)F)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IP6K1 Q92551 1/20 0.60
IP6K3 Q96PC2 1/20 0.60
IP6K2 Q9UHH9 1/20 0.60
ESR1 P03372 9/20 0.57
THRB P10828 1/20 0.56
ATM Q13315 1/20 0.56
CYP2D6 P10635 1/20 0.55
KMT2A Q03164 1/20 0.54
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
HDAC1 Q13547 2/20 0.49
HDAC8 Q9BY41 2/20 0.49
AURKA O14965 1/20 0.49
TPX2 Q9ULW0 1/20 0.49
HCAR2 Q8TDS4 2/20 0.49
AKR1B10 O60218 1/20 0.49
CA3 P07451 1/20 0.49
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7970105 1.00 IP6K1 (0.60) IP6K1IP6K3IP6K2ESR1THRB
SCHEMBL584591 0.95 THRB (0.61) IP6K1IP6K3IP6K2ESR1THRB
SCHEMBL584592 0.95 THRB (0.61) IP6K1IP6K3IP6K2ESR1THRB
Hydrochloric Acid SCHEMBL27902702 0.93 THRB (0.59) IP6K1IP6K3IP6K2ESR1THRB
SCHEMBL867432 0.85 SRD5A2 (0.50) IP6K1IP6K3IP6K2ESR1THRB
SCHEMBL2672355 0.85 SRD5A2 (0.50) IP6K1IP6K3IP6K2ESR1THRB
SCHEMBL867431 0.85 SRD5A2 (0.50) IP6K1IP6K3IP6K2ESR1THRB
SCHEMBL2672350 0.85 SRD5A2 (0.50) IP6K1IP6K3IP6K2ESR1THRB
SCHEMBL508138 0.83 CA12 (0.55) IP6K1IP6K3IP6K2ESR1CYP2D6
SCHEMBL508136 0.83 CA12 (0.55) IP6K1IP6K3IP6K2ESR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3719004-A1 PYRIDINIUM SALT AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2020-10-07 EP disclosed
US-9198913-B2 Nitroimidazooxazines and their uses in anti-tubercular therapy GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT (US) 2015-12-01 US disclosed
EP-2459571-B1 NITROIMIDAZOOXAZINES AND THEIR USES IN ANTI-TUBERCULAR THERAPY GLOBAL ALLIANCE FOR TB DRUG DEV (US) 2015-03-11 EP disclosed
US-6277502-B1 ORGANOSILICON POLYMERS; LIQUID CRYSALS ROLIC AG (CH) 2001-08-21 US disclosed