Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.57 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.57 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 9/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584591 | 1.00 | THRB (0.61) | THRBATMCYP2D6KMT2AIP6K1 | |
| Hydrochloric Acid SCHEMBL27902702 | 0.98 | THRB (0.59) | THRBATMCYP2D6KMT2AIP6K1 | |
| SCHEMBL7970105 | 0.95 | IP6K1 (0.60) | THRBATMCYP2D6KMT2AIP6K1 | |
| SCHEMBL7970101 | 0.95 | IP6K1 (0.60) | THRBATMCYP2D6KMT2AIP6K1 | |
| SCHEMBL2672355 | 0.89 | SRD5A2 (0.50) | THRBATMCYP2D6KMT2AIP6K1 | |
| SCHEMBL867431 | 0.89 | SRD5A2 (0.50) | THRBATMCYP2D6KMT2AIP6K1 | |
| SCHEMBL2672350 | 0.89 | SRD5A2 (0.50) | THRBATMCYP2D6KMT2AIP6K1 | |
| SCHEMBL867432 | 0.89 | SRD5A2 (0.50) | THRBATMCYP2D6KMT2AIP6K1 | |
| SCHEMBL11211973 | 0.87 | CYP2D6 (0.60) | CYP2D6KMT2AIP6K1IP6K3IP6K2 | |
| SCHEMBL11211974 | 0.87 | CYP2D6 (0.60) | CYP2D6KMT2AIP6K1IP6K3IP6K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976182-B2 | Nucleated polyolefin compositions and methods and uses thereof | BRASKEM S.A. (BR) | 2024-05-07 | — | — | US | disclosed |
| CN-114204120-B | Electrolyte for adapting silicon-carbon cathode of lithium ion battery and application of electrolyte | 华南师范大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-114204120-B | Electrolyte for adapting silicon-carbon cathode of lithium ion battery and application of electrolyte | 华南师范大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-116514790-A | Tri-aromatic heterocyclic piperazine small molecular organic compound targeting STAT3 and application thereof | 华东师范大学 | 2023-08-01 | — | — | CN | disclosed |
| CN-112624927-B | TRPV3 inhibitor and preparation method thereof | 青岛大学 | 2023-07-21 | — | — | CN | disclosed |
| US-20230093653-A1 | NUCLEATED POLYOLEFIN COMPOSITIONS AND METHODS AND USES THEREOF | BRASKEM S.A. (BR) | 2023-03-23 | — | — | US | disclosed |
| WO-2023000398-A1 | LYCORINE β-ARYL ACRYLATE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 山东达因海洋生物制药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| US-11499039-B2 | Nucleated polyolefin compositions and methods and uses thereof | BRASKEM S.A. (BR) | 2022-11-15 | — | — | US | disclosed |
| CN-112691099-B | Application of organic compound in preparation of medicine for treating colon cancer | 青岛大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-114204120-A | Electrolyte adaptive to silicon-carbon cathode of lithium ion battery and application of electrolyte | 华南师范大学 | 2022-03-18 | — | — | CN | disclosed |
| WO-2000071572-A1 | SUBSTITUTED BETA-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 2000-11-30 | — | — | WO | disclosed |
| EP-1045833-A1 | 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS | PFIZER INC. (US) | 2000-10-25 | — | — | EP | disclosed |
| US-6117881-A | POTENT AND SELECTIVE INHIBITORS OF CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE SPECIFIC PHOSPHODIESTERASE | ICOS CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |
| US-6043252-A | A POTENT AND SELECTIVE INHIBITORS OF CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE SPECIFIC PHOSPHODIESTERASE (CGMP-SPECIFIC PDE); TREATING CARDIOVASCULAR DISORDERS AND ERECTILE DYSFUNCTION | ICOS CORPORATION (US) | 2000-03-28 | — | — | US | disclosed |
| US-RE36625-E | Linear and cyclic polymers or oligomers having a photoreactive ethene group | ROLIC AG (CH) | 2000-03-21 | — | — | US | disclosed |
| WO-1999041254-A1 | NOVEL TRIAZOLO(4,5-d)PYRIMIDINE COMPOUNDS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |
| WO-1999035130-A1 | 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-07-15 | — | — | WO | disclosed |
| EP-0912567-A1 | CARBOLINE DERIVATIVES | ICOS CORPORATION (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997043287-A1 | CARBOLINE DERIVATIVES | ICOS CORPORATION (US) | 1997-11-20 | — | — | WO | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |