Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | XIAP | P98170 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970571 | 0.83 | CYP3A4 (0.47) | CYP3A4CYP2C9PKMCYP2C19F2 | |
| SCHEMBL8096850 | 0.81 | CYP3A4 (0.72) | CYP3A4CYP2C9PKMCYP2C19F2 | |
| SCHEMBL27394992 | 0.81 | CYP3A4 (0.72) | CYP3A4CYP2C9PKMCYP2C19F2 | |
| SCHEMBL7975161 | 0.76 | ALDH1A1 (0.51) | CYP3A4CYP2C9PKMCYP2C19F2 | |
| SCHEMBL14969584 | 0.72 | RAB9A (0.53) | ALDH1A1MC4R | |
| SCHEMBL23134470 | 0.72 | F12 (0.46) | CYP3A4CYP2C9PKMCYP2C19F2 | |
| SCHEMBL14963205 | 0.71 | ALDH1A1 (0.49) | CYP3A4CYP2C9PKMCYP2C19ALDH1A1 | |
| SCHEMBL21854806 | 0.71 | TACR1 (0.51) | CYP3A4CYP2C9PKMCYP2C19NPSR1 | |
| SCHEMBL10144672 | 0.69 | CYP3A4 (0.64) | CYP3A4CYP2C9PKMCYP2C19F2 | |
| SCHEMBL7302729 | 0.69 | CYP3A4 (0.64) | CYP3A4CYP2C9PKMCYP2C19F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291464-B1 | POTENTIATION OF THE CHOLINERGIC ACTIVITY; THERAPEUTIC TREATMENT OF AMNESIA, DEMENTIA OR SENILE DEMENTIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |