Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 13/20 | 0.48 |
| ▸ | TRPC6 | Q9Y210 | 12/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7965029 | 0.98 | TRPC3 (0.47) | TRPC3TRPC6KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL7965026 | 0.98 | TRPC3 (0.47) | TRPC3TRPC6KDM1AMAOAMAOB | |
| SCHEMBL8150797 | 0.81 | TRPC6 (0.45) | TRPC3TRPC6KDM1AMAOAMAOB | |
| SCHEMBL7970182 | 0.80 | DPP4 (0.49) | KDM4EMEN1ALDH1A1KMT2ACYP2D6 | |
| SCHEMBL7968115 | 0.77 | KDM1A (0.40) | KDM1AMAOAMAOB | |
| SCHEMBL24530845 | 0.77 | TRPC3 (0.54) | TRPC3TRPC6KDM1A | |
| SCHEMBL24530963 | 0.77 | TRPC3 (0.54) | TRPC3TRPC6KDM1A | |
| SCHEMBL24530819 | 0.77 | TRPC3 (0.54) | TRPC3TRPC6KDM1A | |
| Hydrochloric Acid SCHEMBL7970745 | 0.76 | KDM1A (0.39) | TRPC3TRPC6KDM1AMAOAMAOB | |
| SCHEMBL7955785 | 0.76 | KDM1A (0.46) | KDM1AMAOAMAOBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037354-A | ADMINISTERING PHENYL-SUBSTITUTED THIAZOLIDIN-4-ONE OR OXAZOLIDIN-2-ONE DERIVATIVE TO TREAT BENIGN PROSTATE HYPERPLASIA; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-03-14 | — | — | US | claimed |
| US-6255315-B1 | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-07-03 | — | — | US | disclosed |
| US-6037354-A | ADMINISTERING PHENYL-SUBSTITUTED THIAZOLIDIN-4-ONE OR OXAZOLIDIN-2-ONE DERIVATIVE TO TREAT BENIGN PROSTATE HYPERPLASIA; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-03-14 | — | — | US | disclosed |