Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955122 | 1.00 | HTR1A (0.56) | HTR1ADRD2DRD3DRD1DRD4 | |
| SCHEMBL7955124 | 1.00 | HTR1A (0.56) | HTR1ADRD2DRD3DRD1DRD4 | |
| SCHEMBL7970277 | 1.00 | HTR1A (0.56) | HTR1ADRD2DRD3DRD1DRD4 | |
| SCHEMBL7954803 | 0.89 | HTR1A (0.65) | HTR1ADRD2DRD3 | |
| SCHEMBL7883211 | 0.89 | SIGMAR1 (0.60) | HTR1ADRD2SIGMAR1 | |
| SCHEMBL7954799 | 0.89 | HTR1A (0.65) | HTR1ADRD2DRD3 | |
| SCHEMBL7875569 | 0.89 | SIGMAR1 (0.60) | HTR1ADRD2SIGMAR1 | |
| SCHEMBL7879617 | 0.89 | SIGMAR1 (0.60) | HTR1ADRD2SIGMAR1 | |
| SCHEMBL7875567 | 0.89 | SIGMAR1 (0.60) | HTR1ADRD2SIGMAR1 | |
| SCHEMBL7879091 | 0.89 | SIGMAR1 (0.60) | HTR1ADRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262064-B1 | AN ACTAHYDROBENZO(F)QUINOLINE-BASED COMPOUND | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION | 2001-07-17 | — | — | US | disclosed |
| US-5863928-A | TREATMENT OF PSYCHOTIC DISORDERS, PARKINSON'S DISEASE; SEDATIVES | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION THE STATE OF RHODE ISLAND AND PROVIDENCE PLANTATION. (US) | 1999-01-26 | — | — | US | disclosed |