Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.58 |
| ▸ | NOS1 | P29475 | 2/20 | 0.58 |
| ▸ | NOS2 | P35228 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040771 | 0.87 | NOS3 (0.65) | NOS3NOS1NOS2 | |
| Bromide SCHEMBL6962685 | 0.86 | NOS3 (0.66) | NOS3NOS1NOS2 | |
| SCHEMBL9037888 | 0.82 | NOS3 (0.68) | NOS3NOS1NOS2 | |
| Bromide SCHEMBL6968438 | 0.81 | NOS3 (0.69) | NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL9212822 | 0.81 | NOS3 (0.67) | NOS3NOS1NOS2 | |
| SCHEMBL7596209 | 0.80 | NOS1 (0.59) | NOS3NOS1NOS2 | |
| SCHEMBL15512364 | 0.80 | NOS3 (0.56) | NOS3NOS1NOS2 | |
| SCHEMBL9038965 | 0.77 | NOS3 (0.67) | NOS3NOS1NOS2 | |
| SCHEMBL9038075 | 0.77 | NOS1 (0.80) | NOS3NOS1NOS2 | |
| Bromide SCHEMBL6961351 | 0.76 | NOS3 (0.66) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | claimed |