Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.45 |
| ▸ | NOS2 | P35228 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565797 | 0.90 | QRFPR (0.49) | QRFPRLMNANOS1NOS3NOS2 | |
| SCHEMBL7970386 | 0.89 | LMNA (0.48) | QRFPRLMNANOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL7960596 | 0.88 | LMNA (0.47) | QRFPRLMNANOS1NOS3NOS2 | |
| SCHEMBL22537245 | 0.80 | NOS1 (0.55) | QRFPRLMNANOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL7565786 | 0.78 | QRFPR (0.47) | QRFPRLMNANOS1NOS3NOS2 | |
| SCHEMBL7565218 | 0.77 | QRFPR (0.47) | QRFPRLMNANOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL7568761 | 0.76 | QRFPR (0.46) | QRFPRLMNANOS1NOS3NOS2 | |
| SCHEMBL7562858 | 0.76 | QRFPR (0.71) | QRFPRNOS1NOS3NOS2 | |
| SCHEMBL4393554 | 0.70 | QRFPR (0.60) | QRFPRLMNANOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL4406109 | 0.69 | QRFPR (0.59) | QRFPRLMNANOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046170-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |