Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972073 | 1.00 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL7972146 | 0.99 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL7973888 | 0.99 | HDAC3 (0.55) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7960637 | 0.94 | LMNA (0.57) | LMNAMAPTTP53AGTR1AGTR2 | |
| SCHEMBL7960627 | 0.94 | LMNA (0.57) | LMNAMAPTTP53AGTR1AGTR2 | |
| SCHEMBL7960503 | 0.94 | LMNA (0.57) | LMNAMAPTTP53AGTR1AGTR2 | |
| SCHEMBL7973675 | 0.94 | LMNA (0.57) | LMNAMAPTTP53AGTR1AGTR2 | |
| SCHEMBL7960449 | 0.94 | LMNA (0.57) | LMNAMAPTTP53AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL7973802 | 0.92 | LMNA (0.56) | LMNAMAPTTP53AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL7970449 | 0.92 | LMNA (0.56) | LMNAMAPTTP53AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |