SCHEMBL7970715

SCHEMBL7970715

CC(c1ccc(C#N)cc1)C(NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSS P25774 11/20 0.47
CTSK P43235 11/20 0.47
TRPA1 O75762 3/20 0.46
CTSL P07711 3/20 0.41
CTSB P07858 3/20 0.41
MMP1 P03956 2/20 0.41
MMP2 P08253 2/20 0.41
MMP3 P08254 2/20 0.41
MMP7 P09237 2/20 0.41
MMP9 P14780 2/20 0.41
MMP13 P45452 2/20 0.41
PRSS1 P07477 1/20 0.40
CTSG P08311 1/20 0.40
CTRB1 P17538 1/20 0.40
CMA1 P23946 1/20 0.40
APP P05067 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22304137 1.00 CTSS (0.47) CTSSCTSKTRPA1CTSLCTSB
SCHEMBL22338677 1.00 CTSS (0.47) CTSSCTSKTRPA1CTSLCTSB
SCHEMBL20470212 0.85 CTSS (0.45) CTSSCTSKTRPA1CTSLCTSB
SCHEMBL20470211 0.85 CTSS (0.45) CTSSCTSKTRPA1CTSLCTSB
SCHEMBL2573117 0.84 CTSK (0.45) CTSSCTSKTRPA1APP
SCHEMBL3379781 0.84 CTSK (0.51) CTSSCTSKAPP
SCHEMBL14250689 0.84 CTSK (0.51) CTSSCTSKAPP
SCHEMBL4116995 0.84 CTSK (0.51) CTSSCTSKAPP
SCHEMBL3414715 0.84 CTSK (0.51) CTSSCTSKAPP
SCHEMBL844407 0.84 CTSK (0.51) CTSSCTSKAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284912-B1 Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives LG CHEMICAL, LTD. (KR) 2001-09-04 US disclosed
EP-1043309-A1 Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives LG Chemical Ltd. (KR) 2000-10-11 EP disclosed