Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.65 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | FNTB | P49356 | 5/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500590 | 0.79 | FNTA (0.65) | FNTAPGGT1BL3MBTL1LMNAKCNH2 | |
| SCHEMBL3501216 | 0.79 | FNTA (1.00) | FNTAPGGT1BFNTB | |
| Hydrochloric Acid SCHEMBL7987571 | 0.78 | FNTA (0.64) | FNTAPGGT1BL3MBTL1LMNAKCNH2 | |
| Hydrochloric Acid SCHEMBL7982012 | 0.78 | FNTA (0.98) | FNTAPGGT1BFNTB | |
| SCHEMBL7954270 | 0.75 | FNTA (0.45) | FNTAPGGT1BL3MBTL1KCNH2FNTB | |
| SCHEMBL7966541 | 0.74 | LMNA (0.48) | L3MBTL1LMNAKCNH2 | |
| SCHEMBL2950629 | 0.72 | LMNA (0.71) | L3MBTL1LMNAKCNH2GAA | |
| SCHEMBL26130734 | 0.71 | LMNA (0.48) | L3MBTL1LMNAKCNH2 | |
| SCHEMBL7855826 | 0.70 | LMNA (0.59) | L3MBTL1LMNA | |
| SCHEMBL31270697 | 0.69 | LMNA (0.74) | L3MBTL1LMNAKCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333335-B1 | TO INHIBIT PRENYL-PROTEIN TRANSFERASE AND THE PRENYLATION OF THE ONCOGENE PROTEIN RAS | MERCK & CO., INC. | 2001-12-25 | — | — | US | disclosed |