Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981209 | 0.91 | PDPK1 (0.41) | ALDH1A1HPGDRAB9AMEN1KMT2A | |
| SCHEMBL6971260 | 0.90 | JAK3 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2PDPK1 | |
| SCHEMBL6971265 | 0.90 | JAK3 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2PDPK1 | |
| SCHEMBL6978475 | 0.89 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2AURKA | |
| SCHEMBL6978482 | 0.89 | MEN1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2AURKA | |
| SCHEMBL8189897 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8189893 | 0.88 | ALDH1A1 (0.48) | ALDH1A1HPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8191858 | 0.88 | KIT (0.39) | ALDH1A1HPGDRAB9AMEN1KMT2A | |
| SCHEMBL8191861 | 0.88 | KIT (0.39) | ALDH1A1HPGDRAB9AMEN1KMT2A | |
| SCHEMBL6982734 | 0.88 | PPARG (0.39) | ALDH1A1HPGDKMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169106-B1 | ANTITUMOUR AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-01-02 | — | — | US | disclosed |