Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 4/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988135 | 0.86 | BRD4 (0.53) | BRD4CREBBPPARP1MMP12TSHR | |
| SCHEMBL7000943 | 0.81 | PARP1 (0.37) | BRD4CREBBPPARP1PDE3BPDE3A | |
| SCHEMBL5672049 | 0.79 | PARP1 (0.62) | BRD4CREBBPPARP1PDE3BPDE3A | |
| SCHEMBL7982291 | 0.79 | PARP1 (0.33) | BRD4CREBBPPARP1 | |
| SCHEMBL23552860 | 0.76 | PARP1 (0.45) | BRD4CREBBPPARP1PGR | |
| SCHEMBL7003210 | 0.75 | KMT2A (0.48) | PARP1CHRM1PGRNR3C1AR | |
| SCHEMBL7711230 | 0.71 | PARP1 (0.37) | BRD4CREBBPPARP1CHRM1PDE3B | |
| SCHEMBL7001562 | 0.71 | MAPK9 (0.33) | PARP1TSHRNPSR1ALDH1A1GAA | |
| SCHEMBL7984345 | 0.71 | HSD17B10 (0.43) | BRD4CREBBPPARP1CHRM1PDE3B | |
| SCHEMBL7000474 | 0.71 | PARP1 (0.37) | BRD4CREBBPPARP1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |