Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971002 | 0.79 | BRD4 (0.39) | PARP1BRD4CREBBP | |
| SCHEMBL7988135 | 0.79 | BRD4 (0.53) | PARP1BRD4CREBBP | |
| SCHEMBL5671394 | 0.78 | PARP1 (0.56) | PARP1BRD4CREBBP | |
| SCHEMBL7001562 | 0.77 | MAPK9 (0.33) | PARP1 | |
| SCHEMBL7144708 | 0.76 | PDE3B (0.31) | — | |
| SCHEMBL7711230 | 0.74 | PARP1 (0.37) | PARP1BRD4CREBBP | |
| SCHEMBL7000943 | 0.74 | PARP1 (0.37) | PARP1BRD4CREBBP | |
| SCHEMBL7000985 | 0.70 | KDM4E (0.54) | PARP1 | |
| SCHEMBL7981061 | 0.68 | CREBBP (0.53) | PARP1BRD4CREBBP | |
| SCHEMBL7985936 | 0.68 | PARP1 (0.38) | PARP1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |