Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5238030 | 0.87 | GPR119 (0.47) | GPR119 | |
| SCHEMBL5918999 | 0.86 | GPR119 (0.51) | GPR119 | |
| SCHEMBL16997336 | 0.85 | OPRD1 (0.50) | OPRD1OPRK1GPR119TSHRALOX15 | |
| SCHEMBL16987111 | 0.85 | OPRD1 (0.50) | OPRD1OPRK1GPR119TSHRALOX15 | |
| SCHEMBL1475764 | 0.84 | OPRD1 (0.44) | OPRD1OPRK1GPR119TSHRALOX15 | |
| SCHEMBL2951728 | 0.83 | OPRD1 (0.53) | OPRD1OPRK1GPR119TSHRALOX15 | |
| SCHEMBL1473792 | 0.83 | GPR119 (0.46) | OPRD1OPRK1GPR119TSHRALOX15 | |
| SCHEMBL14716255 | 0.82 | TACR1 (0.58) | OPRD1OPRK1GPR119TSHRALOX15 | |
| SCHEMBL457626 | 0.81 | GPR119 (0.46) | OPRD1OPRK1GPR119 | |
| SCHEMBL21388065 | 0.81 | OPRD1 (0.52) | OPRD1OPRK1GPR119TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255322-B1 | NERVOUS SYSTEM DISORDERS; ALZHEIMER'S DISEASE | PFIZER INC. | 2001-07-03 | — | — | US | disclosed |
| CN-1043759-C | Alpha-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents | PFIZER (US) | 1999-06-23 | — | — | CN | disclosed |
| EP-0594729-A1 | 2-(4-HYDROXYPIPERIDINO)-1-ALKANOL DERIVATIVES AS ANTIISCHEMIC AGENTS | PFIZER INC. (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993002052-A1 | 2-(4-HYDROXYPIPERIDINO)-1-ALKANOL DERIVATIVES AS ANTIISCHEMIC AGENTS | PFIZER INC. (US) | 1993-02-04 | — | — | WO | disclosed |
| CN-1068566-A | 2-(4-hydroxy piperidine subbase)-1-alkanol as antiischemic agents | PFIZER (US) | 1993-02-03 | — | — | CN | disclosed |