SCHEMBL7971189

SCHEMBL7971189

O=C(O)CCC1CC2CCC1C2

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
HSD11B1 P28845 1/20 0.36
EPHX2 P34913 2/20 0.36
HPGD P15428 2/20 0.35
P2RX7 Q99572 1/20 0.35
ATM Q13315 1/20 0.35
EPHX1 P07099 1/20 0.35
ALOX5 P09917 1/20 0.34
CYP2C9 P11712 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11611150 0.90 ALOX5 (0.35) MEN1NPC1RAB9AKMT2APOLB
SCHEMBL32688597 0.89 ALOX5 (0.47) MEN1NPC1RAB9AKMT2APOLB
SCHEMBL2958923 0.87 ALOX5 (0.46) MEN1NPC1RAB9AKMT2APOLB
SCHEMBL11602901 0.86 HSD11B1 (0.38) MEN1NPC1RAB9AKMT2APOLB
SCHEMBL11603911 0.86 MEN1 (0.45) MEN1NPC1RAB9AKMT2APOLB
SCHEMBL10835600 0.82 NPC1 (0.42) MEN1NPC1RAB9AKMT2APOLB
SCHEMBL7529601 0.82 MEN1 (0.40) MEN1NPC1RAB9AKMT2APOLB
SCHEMBL32688715 0.81 NPC1 (0.41) MEN1NPC1RAB9AKMT2APOLB
SCHEMBL32688563 0.79 NPC1 (0.41) MEN1NPC1RAB9AKMT2APOLB
SCHEMBL11603592 0.79 POLB (0.47) MEN1NPC1RAB9AKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS PBC (US) 2026-03-19 US disclosed
US-RE37303-E1 Imidazole compounds and their therapeutic applications INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2001-07-31 US disclosed
US-5559113-A ANTAGONISTS TO HISTAMINE H3 RECEPTORS, SEDATIVES, ANTICONVULSANTS, ANTIULCER AGENTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE 1996-09-24 US disclosed
US-5290790-A Histamine H3 antagonists, psychotropic action NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 1994-03-01 US disclosed
US-4349552-A TREATMENT OF CANCER FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1982-09-14 US disclosed
EP-0010941-B1 5-FLUOROURACIL DERIVATIVES, PREPARATION THEREOF AND THEIR PHARMACEUTICAL COMPOSITIONS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-05-12 EP disclosed
EP-0010941-A1 5-Fluorouracil derivatives, preparation thereof and their pharmaceutical compositions FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-05-14 EP disclosed
US-4091020-A CONDENSATION, CATALYTIC DECARBOXYLATION MERCK & CO., INC. (US) 1978-05-23 US disclosed
US-4065497-A MICROBIOCIDES, ALGICIDES MERCK & CO., INC. (US) 1977-12-27 US disclosed
US-4058625-A Broad spectrum antimicrobial compositions containing tris-(hydroxymethyl)aminomethane and polyamines MERCK & CO., INC. (US) 1977-11-15 US disclosed
US-4035174-A MICROBIOCIDES MERCK & CO., INC. (US) 1977-07-12 US disclosed
US-4033748-A MICROBIOCIDES MERCK & CO., INC. (US) 1977-07-05 US disclosed
US-4003934-A ANTIMICROBIAL AGENTS, ALGAE INHIBITORS MERCK & CO., INC. (US) 1977-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078079-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CBR1, CBR3, TAS2R1 MEN1 3787/4885NPC1 1366/4885RAB9A 3885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.