Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7987802 | 0.99 | PRNP (0.42) | PRNPRXFP1HSD11B1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7970747 | 0.86 | KMT2A (0.44) | PRNPRXFP1HSD11B1CYP3A4HPGD | |
| SCHEMBL717586 | 0.77 | RXFP1 (0.52) | PRNPRXFP1HSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL7971230 | 0.76 | HSD11B1 (0.48) | PRNPRXFP1HSD11B1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7987803 | 0.75 | HSD11B1 (0.47) | PRNPRXFP1HSD11B1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7987838 | 0.71 | TBXAS1 (0.47) | PRNPRXFP1HSD11B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2610250 | 0.70 | RXFP1 (0.61) | PRNPRXFP1HSD11B1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7980629 | 0.70 | PRNP (0.48) | PRNPRXFP1HSD11B1MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL7984560 | 0.70 | PRNP (0.45) | PRNPRXFP1HSD11B1MAPTNPC1 | |
| SCHEMBL29483598 | 0.69 | LIMK1 (0.68) | PRNPRXFP1HSD11B1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | claimed |