Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976235 | 0.95 | TDP1 (0.42) | TDP1ATML3MBTL1ALOX15SMN1; SMN2 | |
| SCHEMBL7062943 | 0.88 | ATM (0.44) | TDP1ATML3MBTL1ALOX15ELANE | |
| SCHEMBL8425998 | 0.84 | TDP1 (0.44) | TDP1ATML3MBTL1SMN1; SMN2ELANE | |
| SCHEMBL10877734 | 0.83 | ZDHHC2 (0.46) | TDP1PRSS1PRSS2PRSS3SIRT1 | |
| SCHEMBL12266041 | 0.82 | METAP2 (0.49) | TDP1ATML3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL10399716 | 0.81 | ATM (0.46) | TDP1ATML3MBTL1ALOX15SMN1; SMN2 | |
| SCHEMBL7973137 | 0.79 | ALDH1A1 (0.50) | TDP1L3MBTL1ELANESIRT1KMT2A | |
| SCHEMBL7971288 | 0.77 | HCAR2 (0.48) | TDP1L3MBTL1SMN1; SMN2PPARGNPC1 | |
| SCHEMBL6305898 | 0.77 | ATM (0.52) | TDP1ATML3MBTL1ALOX15ELANE | |
| SCHEMBL11230296 | 0.76 | GAA (0.44) | TDP1L3MBTL1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |