Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984625 | 0.91 | KDM4E (0.36) | ALDH1A1KDM4EHPGDADRB2APOBEC3A | |
| SCHEMBL7971805 | 0.91 | KDM4E (0.36) | ALDH1A1KDM4EHPGDADRB2APOBEC3A | |
| SCHEMBL7992001 | 0.88 | KDM4E (0.39) | ALDH1A1KDM4EHPGDADRB2APOBEC3A | |
| SCHEMBL7978690 | 0.87 | HSD11B1 (0.36) | KDM4E | |
| SCHEMBL12671345 | 0.87 | TSHR (0.40) | ALDH1A1HPGDCYP2C9CYP2C19HTT | |
| SCHEMBL7981464 | 0.87 | KDM4E (0.36) | ALDH1A1KDM4EHPGDADRB2APOBEC3A | |
| SCHEMBL1417571 | 0.87 | ALPG (0.38) | — | |
| SCHEMBL1418321 | 0.85 | DYRK1A (0.35) | — | |
| SCHEMBL7984529 | 0.82 | DYRK1A (0.35) | — | |
| SCHEMBL7984651 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |