Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7961203 | 0.99 | SMN1; SMN2 (0.53) | SMN1; SMN2HRH3DRD4MAOAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7974459 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2HRH3DRD4MAOAL3MBTL1 | |
| SCHEMBL7961432 | 0.80 | HPGD (0.54) | SMN1; SMN2HRH3DRD4L3MBTL1ALDH1A1 | |
| SCHEMBL7961213 | 0.79 | HRH3 (0.57) | HRH3TSHR | |
| SCHEMBL7971292 | 0.79 | HRH3 (0.41) | HRH3L3MBTL1NPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL7971441 | 0.79 | HRH3 (0.56) | HRH3TSHR | |
| SCHEMBL7971371 | 0.78 | HRH3 (0.44) | HRH3SIGMAR1MEN1KMT2A | |
| SCHEMBL7977198 | 0.76 | ALDH1A1 (0.43) | SMN1; SMN2HRH3TSHRALDH1A1CYP1A2 | |
| SCHEMBL27640973 | 0.73 | HRH3 (0.67) | SMN1; SMN2HRH3L3MBTL1NPC1RAB9A | |
| SCHEMBL7971379 | 0.73 | HRH3 (0.51) | HRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |