Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971371 | 0.83 | HRH3 (0.44) | HRH3MEN1KMT2A | |
| SCHEMBL7974351 | 0.82 | TP53 (0.51) | L3MBTL1GAAMEN1TP53KMT2A | |
| SCHEMBL7972638 | 0.81 | MAPT (0.55) | L3MBTL1GPR119GAAMEN1NPC1 | |
| SCHEMBL7974636 | 0.81 | ITGB3 (0.42) | HRH3ITGB3ITGA2BL3MBTL1GPR119 | |
| SCHEMBL7971379 | 0.81 | HRH3 (0.51) | HRH3 | |
| Hydrochloric Acid SCHEMBL7972774 | 0.80 | HRH3 (0.50) | HRH3 | |
| SCHEMBL7971192 | 0.79 | GPR119 (0.57) | L3MBTL1GPR119GAA | |
| SCHEMBL7972868 | 0.79 | HRH3 (0.41) | HRH3ITGB3ITGA2B | |
| SCHEMBL7971561 | 0.79 | SMN1; SMN2 (0.54) | HRH3L3MBTL1MEN1NPC1TP53 | |
| SCHEMBL7972769 | 0.78 | MAPT (0.47) | HRH3L3MBTL1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |