Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 10/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7565732 | 0.99 | KMT2A (0.43) | KMT2AQRFPRMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7562379 | 0.90 | KMT2A (0.44) | KMT2AQRFPRMEN1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7562377 | 0.88 | KMT2A (0.39) | KMT2AQRFPRMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7570363 | 0.88 | KMT2A (0.43) | KMT2AQRFPRMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7570769 | 0.87 | QRFPR (0.43) | KMT2AQRFPRMEN1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7563160 | 0.86 | KMT2A (0.51) | KMT2AQRFPRMEN1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7568742 | 0.86 | QRFPR (0.43) | KMT2AQRFPRMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7570044 | 0.83 | ALDH1A1 (0.50) | KMT2AQRFPRMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7598787 | 0.83 | KMT2A (0.39) | KMT2AQRFPRMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7973644 | 0.82 | ATM (0.44) | KMT2AQRFPRMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |