Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7599918 | 0.99 | QRFPR (0.40) | QRFPRHSD17B10RAB9ANPC1MAPT | |
| SCHEMBL7598614 | 0.89 | QRFPR (0.41) | QRFPRHSD17B10RAB9ANPC1MAPT | |
| SCHEMBL7600914 | 0.82 | QRFPR (0.39) | QRFPRHSD17B10RAB9ANPC1MAPT | |
| SCHEMBL7973639 | 0.81 | QRFPR (0.46) | QRFPRRAB9ANPC1MAPTNFKB1 | |
| Hydrochloric Acid SCHEMBL7562290 | 0.80 | QRFPR (0.45) | QRFPRRAB9ANPC1MAPTNFKB1 | |
| SCHEMBL7598793 | 0.80 | LMNA (0.42) | QRFPRMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL7600302 | 0.80 | LMNA (0.42) | QRFPRMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL7598693 | 0.76 | KMT2A (0.47) | QRFPRHSD17B10RAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL7563160 | 0.75 | KMT2A (0.51) | QRFPRRAB9ANPC1MAPTLMNA | |
| SCHEMBL14404486 | 0.74 | NOS3 (0.46) | CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |