Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985447 | 0.82 | CHRM2 (0.40) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL9444180 | 0.79 | CHRM2 (0.31) | — | |
| SCHEMBL3531364 | 0.65 | MGAM (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL21987177 | 0.64 | MGAM (0.39) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL16486066 | 0.63 | MGAM (0.42) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL2012180 | 0.63 | MGAM (0.42) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL17501817 | 0.63 | MGAM (0.42) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL14696636 | 0.63 | ALDH1A1 (0.56) | TSHR | |
| SCHEMBL12302197 | 0.62 | NPSR1 (0.40) | TSHR | |
| SCHEMBL19704961 | 0.62 | ALDH1A1 (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014310-A1 | PLEUROMUTILIN β-KETOESTERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | disclosed |