Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971882 | 0.82 | MGAM (0.38) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL7983365 | 0.79 | CHRM2 (0.33) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL3318136 | 0.76 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3 | |
| Bromide SCHEMBL8557420 | 0.75 | CHRM2 (0.36) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7367363 | 0.72 | TP53 (0.35) | CHRM2CHRM4CHRM1CHRM3MGAM | |
| Oxalic Acid SCHEMBL9051874 | 0.72 | CHRM1 (0.41) | CHRM2CHRM4CHRM1CHRM3HSD17B10 | |
| Bromide SCHEMBL8556654 | 0.71 | CHRM2 (0.33) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL8558036 | 0.71 | CHRM2 (0.33) | CHRM2CHRM4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL9585273 | 0.71 | CHRM2 (0.33) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9048771 | 0.70 | CHRM2 (0.43) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014310-A1 | PLEUROMUTILIN β-KETOESTERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | disclosed |