Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.49 |
| ▸ | HTR1A | P08908 | 7/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | HTR6 | P50406 | 6/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7985853 | 0.99 | HTR7 (0.48) | HTR7HTR1ADRD2HTR6KDM1A | |
| SCHEMBL7982288 | 0.96 | HTR7 (0.44) | HTR7HTR1ADRD2HTR6KDM1A | |
| Hydrochloric Acid SCHEMBL7985643 | 0.95 | HTR7 (0.44) | HTR7HTR1ADRD2HTR6KDM1A | |
| SCHEMBL7983159 | 0.92 | HTR7 (0.43) | HTR7HTR1ADRD2HTR6KDM1A | |
| Hydrochloric Acid SCHEMBL7986997 | 0.91 | HTR7 (0.42) | HTR7HTR1ADRD2HTR6KDM1A | |
| SCHEMBL7989146 | 0.91 | HTR7 (0.49) | HTR7DRD2KDM1AHTR4HDAC6 | |
| Hydrochloric Acid SCHEMBL7983742 | 0.90 | HTR7 (0.49) | HTR7DRD2KDM1AHTR4HDAC6 | |
| SCHEMBL7985386 | 0.88 | HTR4 (0.42) | HTR7HTR1ADRD2HTR6KDM1A | |
| Hydrochloric Acid SCHEMBL7972092 | 0.88 | HTR4 (0.42) | HTR7HTR1ADRD2HTR6KDM1A | |
| SCHEMBL7982506 | 0.87 | HTR7 (0.41) | HTR7GSK3BHTR4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |