Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.52 |
| ▸ | CCR5 | P51681 | 15/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.38 |
| ▸ | CCR7 | P32248 | 2/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866956 | 0.92 | CCR2 (0.61) | CCR2CCR5MCHR1CXCR3CCR7 | |
| Hydrochloric Acid SCHEMBL7934142 | 0.92 | CCR2 (0.60) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL7968792 | 0.90 | CCR2 (0.52) | CCR2CCR5CXCR3CCR7CXCR5 | |
| SCHEMBL7971913 | 0.89 | CCR2 (0.62) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL7975082 | 0.88 | CCR2 (0.51) | CCR2CCR5CXCR3CCR7 | |
| SCHEMBL7958806 | 0.88 | CCR2 (0.61) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL7958797 | 0.87 | CCR2 (0.49) | CCR2CCR5CXCR3CCR7 | |
| SCHEMBL7972715 | 0.86 | CCR2 (0.48) | CCR2CCR5 | |
| SCHEMBL7972185 | 0.85 | CCR2 (0.60) | CCR2CCR5CXCR3CCR7CXCR5 | |
| SCHEMBL7922031 | 0.84 | CCR2 (0.55) | CCR2CCR5CXCR3CCR7CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |