Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.49 |
| ▸ | CCR5 | P51681 | 16/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | CCR7 | P32248 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975082 | 0.93 | CCR2 (0.51) | CCR2CCR5GCGRCCR7CXCR3 | |
| SCHEMBL7928215 | 0.91 | CCR2 (0.60) | CCR2CCR5CCR7CXCR3 | |
| SCHEMBL7968792 | 0.90 | CCR2 (0.52) | CCR2CCR5CCR7CXCR3 | |
| Hydrochloric Acid SCHEMBL7975094 | 0.90 | CCR2 (0.59) | CCR2CCR5CCR7CXCR3 | |
| SCHEMBL7975020 | 0.89 | CCR2 (0.49) | CCR2CCR5CCR7CXCR3 | |
| SCHEMBL7969147 | 0.88 | CCR2 (0.57) | CCR2CCR5CCR7CXCR3 | |
| SCHEMBL5208604 | 0.87 | CCR5 (0.63) | CCR2CCR5 | |
| SCHEMBL7972234 | 0.87 | CCR2 (0.52) | CCR2CCR5CCR7CXCR3 | |
| SCHEMBL7972715 | 0.87 | CCR2 (0.48) | CCR2CCR5 | |
| SCHEMBL3036000 | 0.85 | CCR2 (0.58) | CCR2CCR5CCR7CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |