Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | HTT | P42858 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 9/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.43 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.43 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.43 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703800 | 0.83 | KMT2A (0.45) | KMT2AMAPTHTTALDH1A1LMNA | |
| SCHEMBL7709788 | 0.80 | KMT2A (0.47) | KMT2AMAPTHTTALDH1A1LMNA | |
| SCHEMBL7709659 | 0.79 | KMT2A (0.49) | KMT2AMAPTHTTALDH1A1LMNA | |
| SCHEMBL7709797 | 0.76 | KMT2A (0.67) | KMT2AMAPTHTTALDH1A1LMNA | |
| SCHEMBL7706867 | 0.76 | MEN1 (0.47) | KMT2AMAPTHTTALDH1A1LMNA | |
| SCHEMBL7709609 | 0.75 | KMT2A (0.69) | KMT2AMAPTHTTALDH1A1LMNA | |
| SCHEMBL7712199 | 0.72 | KMT2A (0.64) | KMT2AMAPTHTTALDH1A1LMNA | |
| SCHEMBL7706806 | 0.72 | KMT2A (0.62) | KMT2AMAPTHTTALDH1A1LMNA | |
| SCHEMBL7709804 | 0.70 | ERCC1 (0.62) | KMT2AMAPTHTTALDH1A1LMNA | |
| SCHEMBL7709644 | 0.69 | BRD1 (0.60) | KMT2AMAPTHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | claimed |