Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 9/20 | 0.60 |
| ▸ | MME | P08473 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962403 | 1.00 | ECE1 (0.60) | ECE1MMEMEN1KMT2AACE | |
| SCHEMBL7962462 | 0.90 | KLK5 (0.53) | ECE1MMEMEN1KMT2AACE | |
| SCHEMBL7962457 | 0.90 | KLK5 (0.53) | ECE1MMEMEN1KMT2AACE | |
| SCHEMBL7973922 | 0.84 | ECE1 (0.67) | ECE1MMEMEN1KMT2A | |
| SCHEMBL9956802 | 0.81 | CTSS (0.56) | ACEPTPN1PPARAPPARGCTSB | |
| SCHEMBL2983987 | 0.81 | ACE (0.55) | ACEPTPN1PPARAPPARGCTSB | |
| SCHEMBL8660300 | 0.81 | CTSS (0.61) | ACEPTPN1PPARAPPARGCTSB | |
| SCHEMBL13239559 | 0.81 | ACE (0.55) | ACEPTPN1PPARAPPARGCTSB | |
| SCHEMBL25742677 | 0.80 | PTPN1 (0.56) | ACEPTPN1PPARAPPARGCTSB | |
| SCHEMBL66220 | 0.80 | ACE (0.79) | KMT2AACEPTPN1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001077095-A2 | DERIVATIVES OF ALPHA-MERCAPTOACETAMIDE | NOVARTIS AG (CH) | 2001-10-18 | — | — | WO | disclosed |