Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7985967 | 0.99 | LTA4H (0.44) | LTA4HGRIN2BSIGMAR1CCR3DRD4 | |
| SCHEMBL7989635 | 0.99 | LTA4H (0.45) | LTA4HGRIN2BSIGMAR1CCR3DRD4 | |
| Hydrochloric Acid SCHEMBL7973177 | 0.98 | LTA4H (0.44) | LTA4HGRIN2BSIGMAR1CCR3DRD4 | |
| SCHEMBL7982426 | 0.97 | LTA4H (0.47) | LTA4HGRIN2BDRD4HTR2AHTR4 | |
| Hydrochloric Acid SCHEMBL7971795 | 0.96 | LTA4H (0.47) | LTA4HGRIN2BDRD4HTR2AHTR4 | |
| SCHEMBL7981833 | 0.93 | HTR4 (0.47) | LTA4HSIGMAR1HTR2AHTR4GSK3B | |
| Hydrochloric Acid SCHEMBL7986403 | 0.93 | HTR4 (0.47) | LTA4HHTR2AHTR4GSK3BHDAC3 | |
| SCHEMBL7990607 | 0.90 | GRIN2B (0.41) | LTA4HGRIN2BCCR3HTR2AHTR4 | |
| SCHEMBL7986487 | 0.89 | LTA4H (0.42) | LTA4HGRIN2BCCR3HTR2AHTR4 | |
| SCHEMBL7972913 | 0.89 | LTA4H (0.42) | LTA4HGRIN2BCCR3HTR4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |