Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 9/20 | 0.51 |
| ▸ | FNTB | P49356 | 8/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | NRAS | P01111 | 1/20 | 0.46 |
| ▸ | HRAS | P01112 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830749 | 0.88 | FNTA (0.67) | LMNAFNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL7842570 | 0.87 | FNTA (0.63) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL7831554 | 0.84 | POLB (0.60) | FNTAFNTBPGGT1BPOLBMEN1 | |
| SCHEMBL7839160 | 0.84 | NPSR1 (0.53) | NPSR1MAPK1GAAALDH1A1LMNA | |
| SCHEMBL7973979 | 0.79 | FNTA (0.63) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7839218 | 0.79 | FNTA (0.65) | FNTAFNTBPGGT1BNRASHRAS | |
| Trifluoroacetic Acid SCHEMBL7974573 | 0.79 | FNTA (0.60) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7843273 | 0.78 | FNTA (0.65) | FNTAFNTBPGGT1BNRASHRAS | |
| SCHEMBL7843356 | 0.77 | FNTA (0.64) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| Trifluoroacetic Acid SCHEMBL7960853 | 0.77 | FNTA (0.53) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248756-B1 | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |