Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7982356 | 0.99 | APP (0.37) | APPHRH3F2F10MCHR1 | |
| SCHEMBL7983600 | 0.93 | MCHR1 (0.40) | MCHR1SMN1; SMN2TYRO3KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7985496 | 0.92 | MCHR1 (0.39) | MCHR1SMN1; SMN2TYRO3KDM4EALDH1A1 | |
| SCHEMBL7986336 | 0.92 | SLC6A2 (0.41) | MCHR1SMN1; SMN2HTR1DHTR1BTYRO3 | |
| SCHEMBL7972387 | 0.92 | SLC6A2 (0.41) | MCHR1SMN1; SMN2HTR1DHTR1BTYRO3 | |
| Hydrochloric Acid SCHEMBL7986019 | 0.91 | SLC6A2 (0.41) | MCHR1SMN1; SMN2HTR1DHTR1BTYRO3 | |
| Hydrochloric Acid SCHEMBL7972006 | 0.91 | SLC6A2 (0.41) | MCHR1SMN1; SMN2HTR1DHTR1BTYRO3 | |
| SCHEMBL7986609 | 0.89 | DRD3 (0.44) | HDAC6SMN1; SMN2DRD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7981722 | 0.88 | DRD3 (0.44) | HDAC6SMN1; SMN2DRD3ALDH1A1 | |
| SCHEMBL7984706 | 0.87 | DRD3 (0.42) | HDAC6SMN1; SMN2DRD3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |