Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7981722 | 0.99 | DRD3 (0.44) | DRD3LMNATP53NR4A1MAPK1 | |
| SCHEMBL7984706 | 0.97 | DRD3 (0.42) | DRD3LMNATP53NR4A1MAPK1 | |
| SCHEMBL7986218 | 0.97 | DRD3 (0.48) | DRD3LMNATP53NR4A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7982703 | 0.97 | DRD3 (0.42) | DRD3LMNATP53NR4A1MAPK1 | |
| Hydrochloric Acid SCHEMBL7983764 | 0.96 | DRD3 (0.47) | DRD3LMNATP53NR4A1MAPK1 | |
| SCHEMBL7985583 | 0.93 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7983892 | 0.92 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7984736 | 0.90 | SMYD2 (0.46) | ALDH1A1CYP2D6 | |
| SCHEMBL7987161 | 0.90 | SMYD2 (0.42) | SMN1; SMN2ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL7971940 | 0.90 | SMYD2 (0.41) | SMN1; SMN2ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |