Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7985496 | 0.99 | MCHR1 (0.39) | MCHR1SLC6A2SLC6A4SLC6A3TYRO3 | |
| SCHEMBL7986336 | 0.96 | SLC6A2 (0.41) | MCHR1SLC6A2SLC6A4SLC6A3TYRO3 | |
| SCHEMBL7972387 | 0.96 | SLC6A2 (0.41) | MCHR1SLC6A2SLC6A4SLC6A3TYRO3 | |
| Hydrochloric Acid SCHEMBL7972006 | 0.95 | SLC6A2 (0.41) | MCHR1SLC6A2SLC6A4SLC6A3TYRO3 | |
| Hydrochloric Acid SCHEMBL7986019 | 0.95 | SLC6A2 (0.41) | MCHR1SLC6A2SLC6A4SLC6A3TYRO3 | |
| SCHEMBL7972522 | 0.93 | APP (0.37) | MCHR1TYRO3SMN1; SMN2ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7982356 | 0.92 | APP (0.37) | MCHR1TYRO3SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7984736 | 0.88 | SMYD2 (0.46) | CYP2D6SMAD3ALDH1A1GAASMYD2 | |
| Hydrochloric Acid SCHEMBL7981574 | 0.87 | SMYD2 (0.45) | CYP2D6SMAD3ALDH1A1GAASMYD2 | |
| SCHEMBL7985583 | 0.87 | ALDH1A1 (0.43) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |