Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968717 | 0.89 | KIF11 (0.46) | KIF11MAPTCYP1A1CYP1B1PTPN5 | |
| SCHEMBL6026268 | 0.85 | CFTR (0.39) | MAPTALDH1A1POLBHSD17B10CCNC | |
| SCHEMBL7539856 | 0.83 | ABCG2 (0.37) | KIF11MAPTPOLBPTPN1 | |
| SCHEMBL7968670 | 0.80 | KIF11 (0.42) | KIF11ARNOTUMKDM4EALDH1A1 | |
| SCHEMBL7956413 | 0.73 | CFTR (0.39) | MAPTALDH1A1CYP2C19HSD17B10 | |
| SCHEMBL6026628 | 0.73 | MEN1 (0.37) | ARNOTUMALDH1A1CYP1A2POLB | |
| SCHEMBL6026391 | 0.72 | MCL1 (0.42) | MAPTNOTUMALDH1A1POLBHSD17B10 | |
| SCHEMBL6027688 | 0.71 | CYP3A4 (0.40) | MAPTALDH1A1HSD17B10PTPN1 | |
| SCHEMBL1044865 | 0.71 | KIF11 (0.61) | KIF11CYP1A1CYP1B1ARMAOB | |
| SCHEMBL13019482 | 0.71 | KIF11 (0.61) | KIF11CYP1A1CYP1B1ARMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |