Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 14/20 | 0.52 |
| ▸ | MAOB | P27338 | 14/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962725 | 0.92 | SMN1; SMN2 (0.58) | SMN1; SMN2MAOAMAOBPPARA | |
| SCHEMBL7972644 | 0.90 | SMN1; SMN2 (0.56) | SMN1; SMN2MAOAMAOBPPARA | |
| SCHEMBL3275944 | 0.79 | MAOB (0.55) | MAOAMAOBPRKCIBAZ2B | |
| SCHEMBL7962734 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2PPARA | |
| SCHEMBL11727398 | 0.77 | MAOB (0.53) | MAOAMAOBPRKCIBAZ2B | |
| SCHEMBL21052075 | 0.77 | MAOB (0.54) | MAOAMAOBADAMTS4MMP2MMP13 | |
| SCHEMBL7520647 | 0.76 | ALOX15 (0.68) | MAOAMAOBPRKCI | |
| SCHEMBL7953934 | 0.76 | MAOB (0.55) | MAOAMAOBADAMTS4MMP2MMP13 | |
| SCHEMBL17361474 | 0.76 | MAOA (0.55) | MAOAMAOBPRKCIBAZ2B | |
| SCHEMBL6825249 | 0.76 | MAOB (0.66) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |