Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 5/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 5/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.30 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.30 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674686 | 0.74 | GHSR (0.48) | GHSRRENCTSS | |
| SCHEMBL5246274 | 0.65 | GHSR (0.87) | GHSR | |
| SCHEMBL5246285 | 0.65 | GHSR (0.87) | GHSR | |
| Hydrochloric Acid SCHEMBL5250982 | 0.65 | GHSR (0.86) | GHSR | |
| Hydrochloric Acid SCHEMBL5246636 | 0.65 | GHSR (0.86) | GHSR | |
| Hydrochloric Acid SCHEMBL5246628 | 0.65 | GHSR (0.86) | GHSR | |
| SCHEMBL5254218 | 0.63 | GHSR (0.71) | GHSRCTSSSCN9A | |
| SCHEMBL5254220 | 0.63 | GHSR (0.71) | GHSRCTSSSCN9A | |
| SCHEMBL5254225 | 0.63 | GHSR (0.71) | GHSRCTSSSCN9A | |
| SCHEMBL6217630 | 0.62 | GHSR (0.42) | GHSRMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313140-B1 | ADMINISTERING TO A HUMAN OR OTHER ANIMAL PYRAZOLOPYRIMIDINE DERIVATIVE FOR PROPHYLAXIS OR THERAPY OF DISEASE OR CONDITION WHICH MAY BE TREATED OR PREVENTED BY GROWTH HORMONE | PFIZER INC. | 2001-11-06 | — | — | US | disclosed |