Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546683 | 0.89 | MEN1 (0.59) | MEN1KMT2ATDP1MAPTCRHBP | |
| SCHEMBL7974460 | 0.87 | MEN1 (0.66) | MEN1KMT2ATDP1MAPTCRHBP | |
| SCHEMBL222442 | 0.86 | MEN1 (0.82) | MEN1KMT2ATDP1MAPTCRHBP | |
| SCHEMBL11553628 | 0.85 | L3MBTL1 (0.55) | MEN1KMT2ATDP1MAPTCRHBP | |
| SCHEMBL15391952 | 0.85 | TDP1 (0.79) | MEN1KMT2ATDP1MAPTCRHBP | |
| SCHEMBL5166263 | 0.84 | TDP1 (0.66) | KMT2ATDP1MAPTL3MBTL1MAPK1 | |
| SCHEMBL6701399 | 0.84 | TDP1 (0.74) | MEN1KMT2ATDP1MAPTL3MBTL1 | |
| SCHEMBL11547932 | 0.83 | L3MBTL1 (0.54) | MEN1KMT2ATDP1MAPTCRHBP | |
| SCHEMBL11549198 | 0.83 | L3MBTL1 (0.54) | MEN1KMT2ATDP1MAPTCRHBP | |
| SCHEMBL11546988 | 0.83 | L3MBTL1 (0.54) | MEN1KMT2ATDP1MAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |