Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973009 | 0.87 | MEN1 (0.76) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL7432275 | 0.84 | MEN1 (0.91) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL11550154 | 0.84 | MAPT (0.60) | MEN1KMT2AMAPTTDP1L3MBTL1 | |
| SCHEMBL11550791 | 0.84 | MAPT (0.60) | MEN1KMT2AMAPTTDP1L3MBTL1 | |
| SCHEMBL14097352 | 0.82 | MEN1 (0.71) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL7429207 | 0.81 | TDP1 (0.91) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL11553628 | 0.81 | L3MBTL1 (0.55) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL5054312 | 0.81 | MAPT (0.85) | MEN1KMT2AMAPTTDP1L3MBTL1 | |
| SCHEMBL5883644 | 0.81 | MEN1 (0.69) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL7437760 | 0.81 | MEN1 (0.69) | MEN1KMT2AMAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |