Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518552 | 0.89 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL25412944 | 0.85 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL13440151 | 0.82 | CYP19A1 (0.52) | MAPTALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL30910450 | 0.82 | HTT (0.38) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2060325 | 0.82 | CA12 (0.48) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL7429642 | 0.82 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL13440156 | 0.80 | CYP19A1 (0.55) | MAPTALDH1A1TDP1CYP3A4ALOX15 | |
| SCHEMBL27103147 | 0.79 | RAB9A (0.40) | MAPTMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL27924546 | 0.79 | CYP19A1 (0.58) | ALDH1A1TDP1CYP3A4ALOX15TP53 | |
| SCHEMBL15304420 | 0.79 | MAPT (0.43) | MAPTMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |