SCHEMBL7973147

SCHEMBL7973147

O=S(=O)(NCc1ccccn1)c1nc2ccc(-c3ccc[nH]3)cc2[nH]1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.43
CCNE1 P24864 1/20 0.43
CDK2 P24941 1/20 0.43
CDK5 Q00535 1/20 0.43
CDK5R1 Q15078 1/20 0.43
PRMT1 Q99873 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5330672 0.80 L3MBTL1 (0.57) L3MBTL1MEN1KMT2AALDH1A1CCNE1
SCHEMBL563423 0.73 QPCT (0.37) L3MBTL1ALDH1A1POLBSMN1; SMN2
SCHEMBL28639616 0.66 CDK2 (0.38) MEN1KMT2AALDH1A1POLBCDK2
SCHEMBL5711769 0.64 L3MBTL1 (0.54) L3MBTL1ALDH1A1POLBSMN1; SMN2
SCHEMBL1873887 0.64 PRMT1 (0.77) L3MBTL1MEN1KMT2AALDH1A1POLB
SCHEMBL23416275 0.63 NAMPT (0.54) L3MBTL1ALDH1A1PRMT1SMN1; SMN2
SCHEMBL22639873 0.63 MEN1 (1.00) L3MBTL1MEN1KMT2AALDH1A1POLB
SCHEMBL29393622 0.63 MEN1 (1.00) L3MBTL1MEN1KMT2AALDH1A1POLB
SCHEMBL29543642 0.63 POLB (0.76) L3MBTL1MEN1KMT2AALDH1A1POLB
SCHEMBL14712377 0.63 PRMT1 (0.66) L3MBTL1ALDH1A1POLBPRMT1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6280773-B1 ACTIVE INGREDIENT, ALKALI STABILIZER AND WATER SOLUBLE POLYMER IL YANG PHARM. CO., LTD. (KR) 2001-08-28 US disclosed