Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10705942 | 0.77 | DGAT1 (0.48) | GSK3BMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL2457533 | 0.72 | QPCT (0.54) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL29770331 | 0.71 | ALDH1A1 (0.61) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL2105330 | 0.71 | ALDH1A1 (0.61) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL29822916 | 0.70 | ALDH1A1 (0.37) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL28822617 | 0.70 | ALDH1A1 (0.37) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL26265589 | 0.69 | ABL1 (0.49) | CDK2GSK3AGSK3BNPC1NT5E | |
| SCHEMBL2457170 | 0.69 | AHR (0.52) | CDK2GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL11349507 | 0.69 | KDM4E (0.55) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| 2-Mercaptobenzimidazole SCHEMBL38651818 | 0.68 | ALDH1A1 (0.58) | GSK3AGSK3BMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113582973-B | Preparation method of thioether | 丽珠医药集团股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-113582973-A | Preparation method of thioether | 丽珠医药集团股份有限公司 | 2021-11-02 | — | — | CN | disclosed |